Answer the questions below and then click the button. The next page will mark your answers and show you how well you have done compared with the previous people who have taken the tests.
Which design of trial would fulfil the following criteria? Usually Phase I Single Arm non-comparative uncontrolled Recruit small group of subjects Conduct trial Assess number of patients with certain event (e.g. toxicity) Compare this number to the decision rule If acceptable increase dosage and repeat with a new set of subjects
Which design of trial best describes the following criteria? Usually Phase I or II Uses a prior knowledge about the outcomes to treatment Patients are treated in the trial The analysis combines the prior knowledge with the trial data This ‘updates’ the prior knowledge to generate the results
Which design of trial best describes the following criteria?
What type of design would fulfil the following criteria?
Usually Phase II or III one group assigned treatment A one group assigned treatment B one group assigned A and B in combination one group assigned neither A or B Compare A vs B, A vs A+B, B vs A+B etc etc
Which trial design can be described by the following criteria: Usually Phase II Determine R1 – level of efficacy where trial is stopped and drug is ‘failed’ N – number of patients initially recruited Recruit N patients Generate results from N patients and compare with R1 If R1 is exceeded continue and recruit more subjects If R1 is not achieved then stop
Which trial design can be described by the following criteria:
